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gemcitabine gemoxen injection
- Manufacturer BEACON PHARMACEUTICALS
- Product Code: Gemoxen Injection
Brand Name: Gemoxen
International Brand Name: Gemzar
Active Ingredient: Gemcitabine Injection
Manufacturer: Beacon Pharmaceutical Co. Ltd.
Packing: Pack of 1 Vial
Country of Origin: Bangladesh
ovarian cancer: gemcitabine in combination with carboplatin is indicated for the treatment of patients with advanced ovarian cancer that has relapsed at least 6 months after completion of platinum-based therapy.
breast cancer: gemcitabine in combination with paclitaxel is indicated for the first-line treatment of patients with metastatic breast cancer after failure of prior anthracycline-containing adjuvant chemotherapy unless anthracyclines were clinically contraindicated.
non-small cell lung cancer: gemcitabine is indicated in combination with cisplatin for the first-line treatment of patients with inoperable, locally advanced (stage iiia or iiib), or metastatic (stage iv) non-small cell lung cancer.
pancreatic cancer: gemcitabine is indicated as first-line treatment for patients with locally advanced (nonresectable stage ii or stage iii) or metastatic (stage iv) adenocarcinoma of the pancreas. gemcitabine is indicated for patients previously treated with 5-fu.
bone marrow suppression is manifested by leukopenia, thrombocytopenia, anaemia and myelosuppression. mild gi effects; rashes; renal impairment, pulmonary toxicity, influenza-like symptoms; interstitial pneumonia, pulmonary oedema. proteinuria, haematuria and haemolytic uraemic syndrome. elevation of serum transaminase.
precautions & warnings:
children, hepatic and renal impairment. may impair the ability to drive or operate machinery. discontinue on 1st sign of microangiopathic haemolytic anaemia. prolonged infusion time (>60 minutes) and more frequent than weekly dosing may increase toxicity. monitor cbc before every dose. increased risk of the haemolytic uraemic syndrome and/or thrombocytopenic purpura which may lead to irreversible renal failure.
store at 25° c.
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